Doug Phanstiel  Associate Professor

Cell Biology & Physiology  |  Thurston Arthritis Research Center  |  Genetics and Molecular Biology  |  douglas_phanstiel@med.unc.edu

We employ advanced genomic techniques, genome editing methods, and bioinformatic analyses to study the mechanisms of long-range gene regulation and the role of 3D chromatin architecture in cellular development and function.

Erika Deoudes  Visualization Specialist

ed@erikadudes.com

I create graphics to communicate the lab's interests and results with maximum clarity. I also contribute to the design of visualization software and to the investigation of animal-free media in cell culture.

Marielle Bond  Graduate Student

Genetics & Molecular Biology  |  B.S. University of North Carolina at Chapel Hill  |  marielle@live.unc.edu

I am studying the mechanisms governing changes in 3D chromatin structure and am using this information to identify novel risk genes for Alzheimer's Disease.

Yoseli Quiroga  Postdoctoral Fellow

Ph.D. National University of La Plata - Argentina  |  B.S. National University of La Plata - Argentina  |  yoseli@live.unc.edu

I use iPS-derived brain cells to study 3D chromatin structure and gene regulation in the context of Alzheimer's Disease.

Sarah Parker  Graduate Student

Bioinformatics & Computational Biology  |  B.S. Pepperdine University  |  sarmae@live.unc.edu

I design, develop, and utilize software to analyze and visualize genomic data to investigate processes related to 3D chromatin structure.

Susan D'Costa  Research Scientist

Thurston Arthritis Research Center  |  Ph.D. North Carolina State University  |  susan_dcosta@med.unc.edu

I use low and high throughput genome editing approaches to understand gene regulation during cellular activation.

JP Flores  Graduate Student

Bioinformatics & Computational Biology  |  B.A. Occidental College  |  jflores@unc.edu

I study the role of phase separation in shaping 3D chromatin structure in health and disease.

Jess Byun  Graduate Student

Bioinformatics & Computational Biology  |  M.S. University of Utah  |  sbyun@unc.edu

I use multi-omics approaches to undertand the molecular mechanisms driving Osteoarthritis.

Zack Drum  Postdoctoral Fellow

PhD Wesleyan University  |  zdrum@unc.edu

I investigate the role of phase separation in driving gene expression and shaping 3D chromatin structure in cancer.

Yijia Wu  Research Assistant

Thurston Arthritis Research Center  |  M.S Case Western Reserve University  |  yijiawu@ad.unc.edu

I am studying gene regulation in Alzheimer’s diseases by using iPS-derived brain cell models and high-throughput genomic technologies.

Doris Cruz Alonso  PREP Scholar

B.S. Northeastern University  |  doris_cruz-alonso@med.unc.edu

Tooba Rashid  MD/PhD Student

Bioinformatics and Computational Biology  |  B.S. North Carolina State  |  tooba_rashid@med.unc.edu

I study the mechanisms that underly dysregulation of 3D chromatin structure in cancer.

Sylvie Parkus  Research Technician

M.S. The University of Sheffield  |  sylvie_parkus@med.unc.edu

Jez Burgess  Postdoctoral Research Associate

Ph.D. Mayo Clinic School of Biomedical Sciences  |  jeremy_burgess@med.unc.edu

I am developing tools and approaches to dissect cell type specific contributions in iPSC derived, complex models of Alzheimer's disease.

Emma Klein  Graduate Student

Bioinformatics and Computational Biology  |  B.S. Emory University emrklein@unc.edu

I study the underlying mechanisms of osteoarthritis using genome wide association studies (GWAS) and integrative genomics, aiming to identify causal variants and genes contributing to disease risk.